Global B2B buy sell marketplace: bytrade.com Office Space Get organized and set aside an area of your home that is specifically for your business. Be sure that the space is professional in appearance if your business requires visits from clients. Decorate your office space with furniture that is comfortable, especially if your business requires that you do a lot of sitting. Structure Determine the structure of your business. If you're a sole proprietor, you are responsible for all the debts of the business, so if a creditor sues you, your personal assets are at risk. If you incorporate your business, your personal assets are kept separate from the business assets. License Check with the county clerk's office in your area to see if any licenses are required to operate your business out of your home. Certain items, such as explosives and medical products, cannot be produced out of the home. Check your city's regulations and be sure that your business adheres to all the laws and regulations of the sale of business products. Taxes and Insurance Keep in mind that you may owe estimated taxes to avoid IRS penalties. Contact your homeowner's insurance agent and update your policy to include coverage for your business office equipment. You also should consider having business or disability insurance in the event that you are unable to operate your business because an accident, a fire or other catastrophe.