What are the best color combinations that you have ever seen? Everytime I make a website design, I try to avoid too much of yellow and pink. yellow simply donot project out well in computer screens and pink gives the male users a feeling that the so said site is not for them, but for ladies. It has evolved into a sex specific color to say. I usually go with blue and white or ochre and white as both colors are quite soothing to eyes and donot tax your eyeballs even after staring at them for too long!