It's a BIG YES!
Because craiglist is a great place to find a job. It has good opportunity for local postings and part-time jobs.I would suggest you to be careful on the oppotunities that is suspicious, but I know lot of people who have succcessfully found jobs on craiglist. Indeed, I found my job on craiglist and I am very happy with it. You should be careful of any job that sounds too good to be true. If they guarantee you extravagant opportunities and an unbelievable salary, it may not be credible.
Plenty employers posts on craiglist. If you think about it from the job poster's perspective, it is a simple selection. Job hunters are having difficulties to search through the open market format of craiglist, but if you give effort you can probably find something GREAT!